Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129843 | 0.85 | PKM (0.46) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL20129857 | 0.82 | MAPT (0.49) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL1826738 | 0.82 | KCNQ2 (0.60) | RAB9ANPC1KMT2AMAPTALDH1A1 | |
| SCHEMBL20129854 | 0.82 | NPC1 (0.46) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL15172817 | 0.81 | MAPT (0.55) | L3MBTL1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL20129856 | 0.78 | PKM (0.41) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL17761732 | 0.78 | ALDH1A1 (0.60) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL8966767 | 0.78 | KCNQ3 (0.54) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL15538708 | 0.78 | MAPT (0.52) | PKML3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL20129848 | 0.78 | THRB (0.42) | PKML3MBTL1RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013011518-A1 | PROCESS FOR THE PREPARATION OF RETIGABINE OF THE FORMULA I AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-01-24 | — | — | WO | claimed |