SCHEMBL92729

SCHEMBL92729

COCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 2/20 0.46
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
TOP1 P11387 1/20 0.33
MGAM O43451 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2297555 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL4996629 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL19741239 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6700235 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1668363 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1964137 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL11559107 0.97 TDP1 (0.60) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL7789495 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL18264410 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL18877220 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
US-9981998-B2 Water-soluble acetaminophen analogs ACORDA THERAPEUTICS, INC. (US) 2018-05-29 US claimed
US-9951001-B2 Hepatoprotectant acetaminophen mutual prodrugs ACORDA THERAPEUTICS, INC. (US) 2018-04-24 US claimed
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. 2018-03-29 US claimed
US-20160326107-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS NEUROGESX, INC. 2016-11-10 US claimed
US-20160264605-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS NEUROGESX, INC. 2016-09-15 US claimed
US-8735376-B2 Carbonate prodrugs and methods of using the same ACORDA THERAPEUTICS, INC. (US) 2014-05-27 US claimed
US-20110263545-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS ACORDA THERAPEUTICS, INC. 2011-10-27 US claimed
US-20110212926-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS NEUROGESX, INC. (US) 2011-09-01 US claimed
US-20110212927-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. (US) 2011-09-01 US claimed
JP-2011520977-A 2011-07-21 JP claimed
EP-2291348-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS Neurogesx, Inc. (US) 2011-03-09 EP claimed
EP-2291084-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME Neurogesx, Inc. (US) 2011-03-09 EP claimed
EP-2285419-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS Neurogesx, Inc. (US) 2011-02-23 EP claimed
WO-2009143297-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. (US) 2009-11-26 WO claimed
WO-2009143295-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS NEUROGESX, INC. (US) 2009-11-26 WO claimed
WO-2009143299-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS NEUROGESX, INC. (US) 2009-11-26 WO claimed
US-20260102294-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION PROCTER & GAMBLE (US) 2026-04-16 US disclosed
EP-0486315-A2 Process for preparing neotrehalose and its uses KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1992-05-20 EP disclosed
EP-0480640-A1 Lactoneotrehalose, and its preparation and uses KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1992-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326107-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS PTGS1, HPGD, PYGL LMNA 3544/4885L3MBTL1 1512/4885TDP1 1999/4885
US-20110212927-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 LMNA 2401/4885L3MBTL1 3401/4885TDP1 1655/4885
US-20110263545-A1 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS PTGS1, HPGD, PYGL LMNA 3544/4885L3MBTL1 1512/4885TDP1 1999/4885
US-20260102294-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION CUTA, SHBG, DSG1 LMNA 2880/4885L3MBTL1 4442/4885TDP1 3090/4885
US-20160264605-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS PTGS1, HPGD, PYGL LMNA 4170/4885L3MBTL1 1822/4885TDP1 2279/4885
US-20110212926-A1 WATER-SOLUBLE ACETAMINOPHEN ANALOGS PTGS1, HPGD, PYGL LMNA 4170/4885L3MBTL1 1822/4885TDP1 2279/4885
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 LMNA 2401/4885L3MBTL1 3401/4885TDP1 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.