SCHEMBL1964137

SCHEMBL1964137

COC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 2/20 0.46
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
TOP1 P11387 1/20 0.33
MGAM O43451 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2297555 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL4996629 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL19741239 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6700235 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1668363 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL92729 1.00 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL11559107 0.97 TDP1 (0.60) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL7789495 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL18264410 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL18877220 0.95 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444883-B1 None US disclosed
CN-111004736-B Bacillus megaterium and application thereof in degrading pyrethroid insecticides 华南农业大学 2021-08-24 CN disclosed
CN-111004736-A Bacillus megaterium and application thereof in degrading pyrethroid insecticides 华南农业大学 2020-04-14 CN disclosed
CN-110499277-A A kind of mould chlamydospore germination medium of red silk wart spore and germination method INST PLANT PROT FAAS 2019-11-26 CN disclosed
US-10106627-B2 Process for the preparation of polymeric biosurfactants COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-10-23 US disclosed
CN-107573359-A One kind contains 1,4:The phenylenediamine monomer of 3,6 2 dewatering hexitol side bases and its preparation and application 吉林大学 2018-01-12 CN disclosed
US-20170065726-A1 NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF CELLMOSAIC INC (US) 2017-03-09 US disclosed
US-9511150-B2 Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof CellMosaic, Inc. (US) 2016-12-06 US disclosed
US-20150322173-A1 PROCESS FOR THE PREPARATION OF POLYMERIC BIOSURFACTANTS COUNCIL OF SCIENTIFIC & INDUSTRAIL RESEARCH (IN) 2015-11-12 US disclosed
EP-1888763-B1 MANNITOL INDUCED PROMOTER SYSTEMS IN BACTERIAL HOST CELLS PFENEX INC (US) 2015-08-12 EP disclosed
US-5856614-A Inbred corn plants 01IZB2 and seeds thereof DEKALB GENETICS CORPORATION (US) 1999-01-05 US disclosed
US-5824848-A Inbred corn plant F361 and seeds thereof DEKALB GENETICS CORPORATION (US) 1998-10-20 US disclosed
US-5824849-A Inbred corn plant 171KI3 and seeds thereof DEKALB GENETICS CORPORATION (US) 1998-10-20 US disclosed
US-5777196-A Inbred corn plant 01CSI6 and seeds thereof DEKALB GENETICS CORPORATION (US) 1998-07-07 US disclosed
US-5777197-A Inbred corn plant 3INI2 and seeds thereof DEKALB GENETICS CORPORATION (US) 1998-07-07 US disclosed
US-5445961-A Preculturing under stresses DEKALB GENETICS CORPORATION (US) 1995-08-29 US disclosed
US-5322789-A Regeneration of monocotyledonous plants; preculturing with a sugar alcohol and colchicine DEKALB PLANT GENETICS (US) 1994-06-21 US disclosed
US-4394502-A Immunotherapeutic agent for tumors comprising lipopolysaccharide as an active component MARUYAMA CHISATO 1983-07-19 US disclosed
US-4329452-A Immunotherapeutic agent for tumors comprising lipopolysaccharide as an active component MARUYAMA CHISATO 1982-05-11 US disclosed
US-4235803-A CYTOSTATIC AGENTS GYOGYSZERKUTATO INTEZET (HU) 1980-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170065726-A1 NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF CD44, ADH1C, EPCAM LMNA 4262/4885L3MBTL1 2520/4885TDP1 4207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.