Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965404 | 0.83 | MAPK14 (0.48) | ALDH1A1KCNH2HTR2ASLC6A4HTR2C | |
| SCHEMBL5071388 | 0.72 | DRD2 (0.41) | KDM4EALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL12126004 | 0.70 | SCD (0.46) | KDM4EKMT2AMEN1HTR2CHTR2B | |
| SCHEMBL13737290 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL643978 | 0.68 | MAPT (0.48) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL2056241 | 0.68 | HRH3 (0.68) | ALDH1A1KMT2AMEN1HTR2ASLC6A4 | |
| SCHEMBL2798804 | 0.68 | HTR1A (0.60) | HTR2AHRH3POLB | |
| SCHEMBL9965465 | 0.67 | NOS2 (0.50) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10174259 | 0.67 | NOS2 (0.50) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7405652 | 0.67 | SIGMAR1 (0.60) | HTR2AHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |