Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778344 | 0.92 | AURKA (0.43) | PPARGAURKANR1H4BDKRB1NPSR1 | |
| SCHEMBL14639984 | 0.90 | PPARG (0.36) | PPARGNR1H4BDKRB1NPSR1RXFP1 | |
| SCHEMBL3872706 | 0.86 | KCNMA1 (0.38) | NPSR1RXFP1FGFR4KDM4E | |
| SCHEMBL1779132 | 0.85 | NR1H4 (0.37) | PPARGAURKANR1H4NPSR1RXFP1 | |
| SCHEMBL1780165 | 0.84 | FGFR4 (0.37) | NPSR1RXFP1DHPSFGFR4KDM4E | |
| SCHEMBL1779700 | 0.82 | AURKA (0.50) | PPARGAURKANR1H4NPSR1RXFP1 | |
| SCHEMBL1779512 | 0.82 | ALDH1A1 (0.46) | AURKABDKRB1KDM4E | |
| SCHEMBL15372479 | 0.82 | HSD17B13 (0.38) | PPARGNR1H4NPSR1RXFP1DHPS | |
| SCHEMBL1778920 | 0.81 | KDR (0.46) | AURKANR1H4KDM4E | |
| SCHEMBL15362133 | 0.81 | AURKA (0.36) | PPARGAURKANR1H4NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009898-A1 | 1H-THIENO[2,3-C]PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-01-25 | — | — | WO | disclosed |