Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.67 |
| ▸ | DRD4 | P21917 | 17/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606272 | 0.94 | MEN1 (0.74) | DRD2DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL8706290 | 0.81 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8707354 | 0.81 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8712569 | 0.80 | DRD4 (1.00) | DRD2DRD4HTR2AHDAC3HDAC4 | |
| SCHEMBL8706135 | 0.79 | DRD2 (1.00) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL7694198 | 0.79 | DRD2 (0.85) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL7694199 | 0.79 | DRD2 (0.85) | DRD2DRD4MCHR1HTR2A | |
| SCHEMBL8711822 | 0.78 | DRD2 (0.85) | DRD2DRD4MEN1KMT2AMCHR1 | |
| SCHEMBL8706273 | 0.78 | DRD2 (0.89) | DRD2DRD4HTR2A | |
| SCHEMBL8706523 | 0.78 | DRD2 (1.00) | DRD2DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |