Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18619443 | 1.00 | SLC6A4 (0.51) | SLC6A4RENFPR1GRK2HTR2C | |
| SCHEMBL7850673 | 0.84 | HTR3A (0.53) | SLC6A4RENSLC6A2SLC6A3 | |
| SCHEMBL1945968 | 0.84 | GRK2 (0.56) | SLC6A4GRK2HTR2CHTR2BSLC6A2 | |
| SCHEMBL4428153 | 0.84 | GRK2 (0.56) | SLC6A4GRK2HTR2CHTR2BSLC6A2 | |
| SCHEMBL1096634 | 0.84 | GRK2 (0.56) | SLC6A4GRK2HTR2CHTR2BSLC6A2 | |
| SCHEMBL7035325 | 0.84 | GRK2 (0.56) | SLC6A4GRK2HTR2CHTR2BSLC6A2 | |
| SCHEMBL7956982 | 0.84 | GRK2 (0.41) | SLC6A4GRK2HTR2BSLC6A2SLC6A3 | |
| SCHEMBL4429628 | 0.84 | GRK2 (0.56) | SLC6A4GRK2HTR2CHTR2BSLC6A2 | |
| SCHEMBL1095996 | 0.83 | SLC18A3 (0.48) | SLC6A4SLC6A2 | |
| SCHEMBL6946523 | 0.83 | SLC18A3 (0.48) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |