Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 14/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641623 | 0.93 | MET (0.42) | METNQO2USP1HCRTR1HCRTR2 | |
| SCHEMBL12241225 | 0.80 | USP1 (0.40) | METNQO2USP1ADORA2A | |
| SCHEMBL14641587 | 0.78 | USP1 (0.41) | METUSP1 | |
| SCHEMBL14641622 | 0.77 | MET (0.52) | METUSP1ADORA2A | |
| SCHEMBL13039502 | 0.76 | MIF (0.50) | — | |
| SCHEMBL14641564 | 0.75 | USP1 (0.43) | METUSP1 | |
| SCHEMBL14641588 | 0.75 | USP1 (0.43) | METUSP1 | |
| SCHEMBL12241151 | 0.73 | MET (0.41) | METNQO2USP1 | |
| SCHEMBL13152788 | 0.72 | MET (0.63) | METNQO2 | |
| SCHEMBL13152685 | 0.69 | MET (0.63) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150551-B1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2013-01-16 | — | — | EP | disclosed |