SCHEMBL146443

SCHEMBL146443

CCN(CC)c1ccc(N=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.58
MAPK1 P28482 4/20 0.58
TSHR P16473 3/20 0.58
TP53 P04637 1/20 0.58
HIF1A Q16665 1/20 0.58
HSD17B10 Q99714 1/20 0.58
ALDH3A1 P30838 1/20 0.54
ALDH1A3 P47895 1/20 0.54
L3MBTL1 Q9Y468 5/20 0.52
TDP1 Q9NUW8 3/20 0.52
GFER P55789 3/20 0.52
RECQL P46063 2/20 0.52
PSMD14 O00487 1/20 0.52
CYP3A4 P08684 1/20 0.52
KDM4E B2RXH2 7/20 0.52
GAA P10253 5/20 0.52
MEN1 O00255 10/20 0.49
KMT2A Q03164 10/20 0.49
MAPT P10636 9/20 0.49
LMNA P02545 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11586430 0.98 ALDH1A1 (0.56) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL12846909 0.94 MAPT (0.54) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL20123341 0.89 GRK6 (0.49) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL9437398 0.89 ALDH1A1 (0.53) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL10025577 0.85 KMT2A (0.51) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL11914191 0.85 ALDH1A1 (0.47) ALDH1A1MAPK1TSHRTP53HIF1A
Hydrochloric Acid SCHEMBL17847422 0.83 KMT2A (0.50) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL28172121 0.83 ALDH1A1 (0.46) ALDH1A1MAPK1TSHRTP53HIF1A
SCHEMBL9437401 0.83 ALDH1A1 (0.54) ALDH1A1MAPK1TSHRTP53HIF1A
Hydrochloric Acid SCHEMBL9015925 0.82 ALDH1A1 (0.44) ALDH1A1MAPK1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12129268-B2 Chiral N-substituted allylic amine compounds UNIVERSITY OF LOUISIANA AT LAFAYETTE (US) 2024-10-29 US claimed
CN-117801392-B Rubber shock pad for tunnel lining and preparation method and application thereof 中裕铁信交通科技股份有限公司 2024-05-14 CN claimed
CN-117844555-A Waterproof type flame-retardant hydraulic oil and preparation method thereof 辽宁海华科技股份有限公司 2024-04-09 CN claimed
CN-117801392-A Rubber shock pad for tunnel lining and preparation method and application thereof 中裕铁信交通科技股份有限公司 2024-04-02 CN claimed
CN-112694683-B Preparation method of acrylate rubber and ethylene propylene diene monomer rubber blended composite rubber 中国铁路经济规划研究院有限公司 2024-01-16 CN claimed
US-11851685-B2 Zwitterion buffer containing compositions and uses in electroanalytical devices and methods ROCHE DIABETES CARE, INC. (US) 2023-12-26 US claimed
CN-112694683-A Preparation method of acrylate rubber and ethylene propylene diene monomer blended composite rubber 中国铁路经济规划研究院有限公司 2021-04-23 CN claimed
CN-110577705-A high-sealing-performance rubber material for pressure sensor and preparation method thereof 天长市宏福电子有限公司 2019-12-17 CN claimed
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US claimed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US claimed
WO-2003070687-A1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS CROMPTON CORPORATION (US) 2003-08-28 WO claimed
US-20030155227-A1 Nitrosophenols and C-nitrosoanilines as polymerization inhibitors CROMPTON CORPORATION 2003-08-21 US claimed
US-6372030-B1 INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID XEROX CORPORATION 2002-04-16 US claimed
EP-0354441-B1 Method for the colorimetric determination of analyte using enzymatic oxydation BOEHRINGER MANNHEIM GMBH (DE) 1995-05-17 EP claimed
US-5286362-A Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially BOEHRINGER MANNHEIM GMBH (DE) 1994-02-15 US claimed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP claimed
US-4675355-A REACTIVE AMINE-CONTAINING NITROSO COMPOUND AND AN HALOGENATED ALKYLBENZENE TO IMPROVE GREEN STRENGTH; TIRES BRIDGESTONE CORPORATION (JP) 1987-06-23 US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12129268-B2 Chiral N-substituted allylic amine compounds HNMT, NNMT, TPMT ALDH1A1 490/4885MAPK1 4221/4885TSHR 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.