Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 15/20 | 0.66 |
| ▸ | PLK3 | Q9H4B4 | 7/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464667 | 0.84 | PLK1 (0.90) | PLK1PLK3TRPV1SLC16A3 | |
| SCHEMBL6838813 | 0.81 | CES2 (0.59) | PLK1TRPV1 | |
| SCHEMBL28808948 | 0.81 | PLK1 (0.97) | PLK1PLK3 | |
| SCHEMBL15170179 | 0.80 | BACE1 (0.59) | — | |
| SCHEMBL6837052 | 0.78 | CES2 (0.57) | TRPV1 | |
| SCHEMBL23657651 | 0.76 | TRPV1 (0.68) | PLK1PLK3TRPV1 | |
| SCHEMBL6836519 | 0.76 | RARB (0.56) | — | |
| SCHEMBL6836850 | 0.76 | RARB (0.56) | — | |
| SCHEMBL6832878 | 0.76 | RARB (0.56) | — | |
| SCHEMBL6838814 | 0.76 | CES2 (0.59) | PLK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (LV) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | LTC4S, LTB4R2, LTB4R | PLK1 3734/4885PLK3 1566/4885TRPV1 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.