Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645817 | 0.89 | KDM4E (0.42) | KDM4EHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL14645997 | 0.86 | ALDH1A1 (0.43) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL14645957 | 0.86 | ALDH1A1 (0.43) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL14645847 | 0.82 | KDM4E (0.46) | KDM4EHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL14645991 | 0.82 | HTT (0.44) | KDM4EHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL2256681 | 0.79 | KDM4E (0.50) | KDM4EHSD17B10MEN1KMT2ATDP1 | |
| SCHEMBL1706723 | 0.79 | KDM4E (0.39) | KDM4EHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL14645980 | 0.78 | ALDH1A1 (0.35) | KDM4EHSD17B10L3MBTL1TDP1GABRP | |
| SCHEMBL28042516 | 0.76 | XDH (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1238859 | 0.76 | KDM4E (0.50) | KDM4EHSD17B10MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729444-B1 | METHOD FOR MANUFACTURING 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2729444-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | Bayer Intellectual Property GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007603-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |