Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235361 | 0.78 | MAOB (0.35) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL28812714 | 0.76 | MAOB (0.36) | MAOBMAOAOPRM1OPRL1 | |
| SCHEMBL1698175 | 0.75 | CA1 (0.37) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL9488195 | 0.69 | OPRM1 (0.36) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL74066 | 0.69 | OPRM1 (0.36) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL13873625 | 0.67 | MAOB (0.35) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL3972311 | 0.67 | MAOB (0.38) | MAOBMAOAOPRM1OPRL1 | |
| SCHEMBL29478279 | 0.67 | MAOB (0.44) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL27906055 | 0.67 | MAOB (0.34) | MAOBMAOAOPRM1OPRK1OPRL1 | |
| SCHEMBL6735829 | 0.67 | CNR1 (0.38) | MAOBMAOACFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9138398-B2 | Cationic alcohols and uses thereof | LIVING PROOF, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20130156719-A1 | CATIONIC ALCOHOLS AND USES THEREOF | LIVING PROOF, INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-8404221-B2 | Cationic alcohols and uses thereof | LIVING PROOF, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120276036-A1 | CATIONIC ALCOHOLS AND USES THEREOF | LIVING PROOF, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| US-8242309-B2 | Cationic alcohols and uses thereof | LIVING PROOF, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| EP-2477486-A1 | CATIONIC ALCOHOLS AND USES THEREOF | Living Proof, Inc. (US) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011035034-A1 | CATIONIC ALCOHOLS AND USES THEREOF | LIVING PROOF, INC. (US) | 2011-03-24 | — | — | WO | disclosed |
| US-20110070179-A1 | CATIONIC ALCOHOLS AND USES THEREOF | LIVING PROOF, INC. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156719-A1 | CATIONIC ALCOHOLS AND USES THEREOF | ADH1A, ADH1C, TRPV1 | MAOB 1454/4885MAOA 1295/4885HTR2A 138/4885 |
| US-20120276036-A1 | CATIONIC ALCOHOLS AND USES THEREOF | ADH1A, ADH1C, TRPV1 | MAOB 1454/4885MAOA 1295/4885HTR2A 138/4885 |
| US-20110070179-A1 | CATIONIC ALCOHOLS AND USES THEREOF | ADH1A, ADH1C, TRPV1 | MAOB 1454/4885MAOA 1295/4885HTR2A 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.