Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958391 | 0.87 | ALDH1A1 (0.50) | ALOX15CYP3A4TSHRACHEALOX5 | |
| SCHEMBL19028058 | 0.82 | ALOX15 (0.46) | ALOX15ACHEALOX5KMT2AMEN1 | |
| SCHEMBL13720135 | 0.81 | GAA (0.50) | ALOX15CYP3A4ACHECREBBPKMT2A | |
| Hydrochloric Acid SCHEMBL4371479 | 0.81 | MEN1 (0.39) | ALOX15CYP3A4PTGDR2ALOX5KMT2A | |
| SCHEMBL28756384 | 0.80 | ACHE (0.50) | ALOX15CYP3A4ACHEKMT2AMEN1 | |
| SCHEMBL31633492 | 0.79 | ALDH1A1 (0.46) | ALOX15CYP3A4TSHRPTGDR2ALOX5 | |
| Hydrochloric Acid SCHEMBL11340459 | 0.79 | CYP3A4 (0.59) | CYP3A4TSHRPTGDR2CREBBPKMT2A | |
| SCHEMBL14143479 | 0.79 | ALOX15 (0.46) | ALOX15CYP3A4TSHRACHEKMT2A | |
| SCHEMBL7904029 | 0.78 | IRAK4 (0.50) | ALOX15CYP3A4TSHRALOX5KMT2A | |
| Hydrochloric Acid SCHEMBL4371476 | 0.78 | PTGDR2 (0.35) | CYP3A4TSHRPTGDR2ALOX5CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013007694-A1 | PRODRUG OF AN ANTI-INFLAMMATORY ACTIVE INGREDIENT | CHEMI S.P.A. (IT) | 2013-01-17 | — | — | WO | disclosed |