SCHEMBL14647140

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647134	0.82	PARP1 (0.50)	PARP1
	SCHEMBL14647113	0.76	HDAC1 (0.42)	PARP1HDAC1HDAC8HDAC6DAO
	SCHEMBL14647144	0.71	GRIK1 (0.34)	PARP1PARP2MAPTFEN1KDM4E
	SCHEMBL14647192	0.67	PARP1 (0.46)	PARP1PARP2MAPTKDM4EALDH1A1
	SCHEMBL14647180	0.66	SMN1; SMN2 (0.51)	MAPTKDM4EALDH1A1
	SCHEMBL14977050	0.62	PARP1 (0.63)	PARP1PARP2PARP3MIF
	SCHEMBL29458471	0.61	PGR (0.54)	HDAC1HDAC8HDAC6DAOPGR
	SCHEMBL1381428	0.60	OPRM1 (0.45)	PARP1PARP2HDAC1HDAC8HDAC6
	SCHEMBL3232088	0.58	AR (0.38)	KDM4EALDH1A1
	SCHEMBL7273946	0.58	IMPDH2 (0.59)	KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.