SCHEMBL14647180

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647202	0.91	MAPT (0.56)	SMN1; SMN2LMNAKDM4ETSHRMAPK1
	SCHEMBL14647178	0.87	MAPT (0.52)	SMN1; SMN2LMNAKDM4ETSHRMAPK1
	SCHEMBL14647179	0.84	ALDH1A1 (0.50)	SMN1; SMN2KDM4ETSHRMAPK1HTT
	SCHEMBL14647229	0.83	SMN1; SMN2 (0.48)	SMN1; SMN2LMNAKDM4ETSHRMAPK1
	SCHEMBL14647261	0.83	MGLL (0.49)	SMN1; SMN2LMNAKDM4ETSHRMAPK1
	SCHEMBL14647161	0.82	MGLL (0.52)	SMN1; SMN2LMNAKDM4ETSHRMAPK1
	SCHEMBL14647218	0.80	MGLL (0.46)	SMN1; SMN2LMNATSHRMAPK1MAPT
	SCHEMBL14647149	0.80	MAPT (0.55)	SMN1; SMN2LMNATSHRMAPK1HTT
	SCHEMBL14647176	0.80	MGLL (0.50)	KDM4ETSHRMAPTMGLL
	SCHEMBL14647232	0.80	SPR (0.52)	SMN1; SMN2LMNAKDM4ETSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.