SCHEMBL14647166

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647239	0.91	KDM4E (0.46)	ADRA1BADRA1DADRA1AHTR1ADRD2
	SCHEMBL15979574	0.90	PARP1 (0.49)	PARP1KCNH2PARP2HTR1ADRD2
	SCHEMBL14647213	0.88	MAPK1 (0.49)	PARP1ADRA1BADRA1DADRA1AHTR1A
	SCHEMBL14647183	0.87	PARP1 (0.46)	PARP1DRD2DRD4DRD3TNK2
	SCHEMBL14647226	0.87	TNKS (0.43)	PARP1HTR1A
	SCHEMBL14647187	0.85	DRD4 (0.43)	PARP1HTR1ADRD2DRD4DRD3
	SCHEMBL14647173	0.83	DRD2 (0.38)	PARP1KCNH2ADRA1BADRA1DADRA1A
	SCHEMBL15979572	0.83	DRD2 (0.47)	PARP1ADRA1BHTR1ADRD2DRD4
	SCHEMBL14647125	0.82	HTR7 (0.52)	PARP1HTR1ADRD2DRD4DRD3
	SCHEMBL14647217	0.82	DRD4 (0.48)	PARP1HTR1ADRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.