SCHEMBL14647239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647166	0.91	PARP1 (0.49)	DRD4DRD3DRD2HTR1AHTR7
	SCHEMBL15979572	0.88	DRD2 (0.47)	KDM4EALDH1A1DRD4DRD2GAA
	SCHEMBL14647183	0.85	PARP1 (0.46)	POLBTSHRDRD4DRD3DRD2
	SCHEMBL15979574	0.85	PARP1 (0.49)	DRD4DRD2HTR1A
	SCHEMBL14647125	0.85	HTR7 (0.52)	KDM4EHSD17B10ALDH1A1DRD4DRD3
	SCHEMBL14647217	0.85	DRD4 (0.48)	HSD17B10TSHRDRD4DRD3DRD2
	SCHEMBL14647226	0.85	TNKS (0.43)	TSHRMEN1KMT2AHTR1A
	SCHEMBL14647223	0.84	SIGMAR1 (0.45)	KDM4EHSD17B10ALDH1A1TSHRGAA
	SCHEMBL14647187	0.84	DRD4 (0.43)	HSD17B10ALDH1A1TSHRDRD4DRD3
	SCHEMBL14647170	0.83	DRD2 (0.59)	DRD4DRD3DRD2GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.