SCHEMBL14647261

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647202	0.90	MAPT (0.56)	MGLLSMN1; SMN2HTTKMT2AMEN1
	SCHEMBL14647161	0.90	MGLL (0.52)	MGLLSMN1; SMN2KMT2AMEN1POLB
	SCHEMBL14647132	0.88	MGLL (0.49)	MGLLSMN1; SMN2HTTUSP2MAPT
	SCHEMBL14647178	0.87	MAPT (0.52)	MGLLSMN1; SMN2HTTKMT2AMEN1
	SCHEMBL14647165	0.87	ALDH1A1 (0.51)	MGLLSMN1; SMN2KMT2AMEN1NAMPT
	SCHEMBL14647232	0.85	SPR (0.52)	MGLLSMN1; SMN2HTTKMT2AMEN1
	SCHEMBL14647149	0.84	MAPT (0.55)	MGLLSMN1; SMN2HTTUSP2MAPT
	SCHEMBL14647121	0.84	PARP1 (0.48)	MGLLSMN1; SMN2NAMPTCYP3A4LMNA
	SCHEMBL14647210	0.84	ALDH1A1 (0.55)	MGLLSMN1; SMN2HTTKMT2AMEN1
	SCHEMBL14647218	0.84	MGLL (0.46)	MGLLSMN1; SMN2KMT2AMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.