SCHEMBL146486

SCHEMBL146486

O=C(OOC(=O)C(O)CO)C(O)CO.[H+]

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.48
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL572817 0.97 OR51E2 (0.50) OR51E2ALDH1A1LMNA
SCHEMBL28995134 0.86 OR51E2 (0.46) OR51E2
SCHEMBL11773175 0.81
SCHEMBL93977 0.79 OR51E2 (0.50) OR51E2ALDH1A1LMNA
SCHEMBL8073397 0.78 OR51E2 (0.39) OR51E2ALDH1A1LMNA
SCHEMBL7108236 0.77
SCHEMBL6249794 0.77 OR51E2 (0.48) OR51E2ALDH1A1LMNA
Water SCHEMBL22418485 0.77 OR51E2 (0.55) OR51E2ALDH1A1LMNA
SCHEMBL4985589 0.77 OR51E2 (0.48) OR51E2ALDH1A1LMNA
SCHEMBL29670664 0.76 PGK1 (0.38) OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268785-B1 STAIN-DISCHARGING AND REMOVING SYSTEM KIMBERLY CLARK CO (US) 2018-04-25 EP claimed
US-20120058059-A1 SINGLE PHASE WHITENING DENTIFRICE COLGATE-PALMOLIVE COMPANY (US) 2012-03-08 US claimed
CN-1933800-A Tooth whitening compositions and methods with reduced peroxide concentration COLGATE PALMOLIVE CO (US) 2007-03-21 CN claimed
US-20260090966-A1 UROLITHIN COMPOSITIONS AMAZENTIS SA (CH) 2026-04-02 US disclosed
EP-3532168-B1 ORAL CARE COMPOSITION COLGATE PALMOLIVE CO (US) 2026-03-25 EP disclosed
US-12582582-B2 Oral care compositions and methods of use COLGATE-PALMOLIVE COMPANY (US) 2026-03-24 US disclosed
US-12582585-B2 Peroxymonosulfate oral whitening compositions COLGATE-PALMOLIVE COMPANY (US) 2026-03-24 US disclosed
EP-4699598-A2 WHITENING COMPOSITIONS AND METHODS FOR INCREASING STABILITY OF THE SAME Colgate-Palmolive Company (US) 2026-02-25 EP disclosed
EP-4673230-A1 FILM FORMING ORAL CARE COMPOSITIONS AND METHODS FOR THE SAME Colgate-Palmolive Company (US) 2026-01-07 EP disclosed
EP-3716933-B1 WHITENING COMPOSITIONS AND METHODS FOR INCREASING STABILITY OF THE SAME COLGATE PALMOLIVE CO (US) 2026-01-07 EP disclosed
EP-3672561-B1 ORAL CARE COMPOSITION COLGATE PALMOLIVE CO (US) 2026-01-07 EP disclosed
US-20050214720-A1 Dental whitening method COLGATE-PALMOLIVE COMPANY 2005-09-29 US disclosed
US-20050210615-A1 Oral care method COLGATE-PALMOLIVE COMPANY 2005-09-29 US disclosed
US-20050207997-A1 Dual component dentifrices and methods of whitening using the same COLGATE-PALMOLIVE COMPANY 2005-09-22 US disclosed
WO-2005072692-A1 DENTAL-BLEACHING COMPOSITIONS AND METHODS WITH REDUCED PEROXIDE CONCENTRATION COLGATE-PALMOLIVE COMPANY (US) 2005-08-11 WO disclosed
US-20050163729-A1 Oral compositions containing peroxide and methods for use COLGATE-PALMOLIVE COMPANY 2005-07-28 US disclosed
US-20050069502-A1 Hydrophobic polymer carrier based liquid tooth whitening composition COLGATE-PALMOLIVE COMPANY 2005-03-31 US disclosed
US-20050063923-A1 contains a polymer carrier; water insoluble; whitening agent is polyvinylpyrrolidone/hydrogen peroxide, liquid hydrogen peroxide, urea peroxide, sodium percarbonate or sodium perborate COLGATE-PALMOLIVE COMPANY 2005-03-24 US disclosed
WO-2005018593-A2 HYDROPHOBIC POLYMER CARRIER BASED LIQUID TOOTH WHITENING COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 2005-03-03 WO disclosed
WO-2005016299-A1 HYDROPHOBIC TOOTH WHITENING SYSTEM AND METHODS OF USE COLGATE-PALMOLIVE COMPANY (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090966-A1 UROLITHIN COMPOSITIONS UTS2R, TAS2R30, TAS2R42 OR51E2 3584/4885ALDH1A1 3820/4885LMNA 3052/4885
US-12582585-B2 Peroxymonosulfate oral whitening compositions KCNN3, KCNN1, POLR1C OR51E2 4542/4885ALDH1A1 4791/4885LMNA 2010/4885
US-12582582-B2 Oral care compositions and methods of use CAB39, CALCOCO2, PROC OR51E2 2707/4885ALDH1A1 3762/4885LMNA 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.