Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HEXA | P06865 | 1/20 | 0.44 |
| ▸ | HEXB | P07686 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650690 | 0.91 | LMNA (0.47) | LMNAMAPK1HPGDALDH1A1HTT | |
| SCHEMBL14650599 | 0.87 | GSK3A (0.45) | LMNAMAPK1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14650534 | 0.86 | LMNA (0.44) | LMNAMAPK1HPGDALDH1A1HTT | |
| SCHEMBL14650604 | 0.84 | TERT (0.42) | LMNAMAPK1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14650602 | 0.84 | TERT (0.42) | HPGDALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL14650630 | 0.84 | CYP1B1 (0.49) | ALDH1A1SMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL14650601 | 0.78 | STAT3 (0.49) | LMNAALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL14650588 | 0.78 | STAT3 (0.51) | LMNAMAPK1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14650611 | 0.77 | CYP1B1 (0.52) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL14650616 | 0.76 | ACHE (0.41) | LMNAMAPK1HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |