Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650602 | 0.89 | TERT (0.42) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL14650630 | 0.89 | CYP1B1 (0.49) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL14650599 | 0.88 | GSK3A (0.45) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL14650616 | 0.85 | ACHE (0.41) | TERTSTAT3HIF1AMAPTLMNA | |
| SCHEMBL14650533 | 0.85 | TERT (0.34) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL31257229 | 0.84 | TERT (0.53) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL14303166 | 0.84 | TERT (0.53) | TERTSTAT3HIF1ACA1CA2 | |
| SCHEMBL14650596 | 0.84 | LMNA (0.52) | MAPTPOLBLMNAMAPK1ALDH1A1 | |
| SCHEMBL14650611 | 0.81 | CYP1B1 (0.52) | TERTSTAT3HIF1AMAPTPOLB | |
| SCHEMBL14650588 | 0.80 | STAT3 (0.51) | TERTSTAT3HIF1AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |