Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650634 | 0.96 | TDP1 (0.43) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650638 | 0.89 | PDE6D (0.41) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650653 | 0.87 | MGLL (0.43) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650677 | 0.86 | KMT2A (0.38) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650706 | 0.81 | MCHR1 (0.37) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650542 | 0.81 | ALDH1A1 (0.36) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650625 | 0.81 | CA2 (0.60) | — | |
| SCHEMBL14650627 | 0.80 | NPC1 (0.42) | KMT2AUSP2MEN1ALDH1A1KDM4E | |
| SCHEMBL14650550 | 0.80 | ALDH1A1 (0.35) | TDP1KMT2AUSP2MEN1ALDH1A1 | |
| SCHEMBL14650641 | 0.80 | TDP1 (0.48) | TDP1KMT2AUSP2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |