Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243189 | 0.82 | L3MBTL1 (0.53) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL12203746 | 0.81 | SMN1; SMN2 (0.56) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL12520053 | 0.79 | ALDH1A1 (0.53) | L3MBTL1HSD17B10SMN1; SMN2POLBLMNA | |
| SCHEMBL11241398 | 0.79 | ALDH1A1 (0.49) | L3MBTL1HSD17B10SMN1; SMN2POLBLMNA | |
| SCHEMBL18016684 | 0.78 | CYP1A2 (0.46) | L3MBTL1SMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL15440675 | 0.76 | CA2 (0.42) | TSHRHSD17B10SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL3549604 | 0.76 | ALDH1A1 (0.36) | L3MBTL1TSHRHSD17B10SMN1; SMN2POLB | |
| SCHEMBL21300279 | 0.76 | L3MBTL1 (0.47) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL13187947 | 0.76 | L3MBTL1 (0.61) | L3MBTL1TSHRSMN1; SMN2POLBLMNA | |
| SCHEMBL12767515 | 0.74 | HSD11B1 (0.47) | L3MBTL1POLBALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718293-B1 | SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS | HUTCHISON MEDIPHARMA LTD (CN) | 2017-10-25 | — | — | EP | disclosed |
| WO-2013010380-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-01-24 | — | — | WO | disclosed |