SCHEMBL146575

SCHEMBL146575

CCO[SiH](CNC1CCCCC1)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 4/20 0.36
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
TSHR P16473 1/20 0.33
DPP7 Q9UHL4 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6059263 0.85 CYP1A2 (0.42) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL125661 0.81 KDM4E (0.41) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL4796418 0.79 KDM4E (0.40) KDM4EALDH1A1POLBMEN1GAA
SCHEMBL15361138 0.78 KDM4E (0.40) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL15360639 0.77 KDM4E (0.39) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL15360811 0.75 GNAI3 (0.39) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL21874986 0.74 THRB (0.33) KDM4EALDH1A1MEN1GAAKMT2A
SCHEMBL1455090 0.73 KDM4E (0.32) KDM4EALDH1A1POLBCYP1A2CYP2D6
SCHEMBL22790769 0.73 KDM4E (0.48) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL22316957 0.73 KDM4E (0.48) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2429720-A2 PHENOLATE ESTER COMPOUNDS Nano-X GmbH (DE) 2012-03-21 EP claimed
US-20120059116-A1 METHOD OF PRODUCING PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2012-03-08 US claimed
WO-2010130241-A2 PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2010-11-18 WO claimed
CN-119866359-A Moisture curable composition and adhesive containing the same 瓦克化学股份公司 2025-04-22 CN disclosed
CN-119403877-A Room temperature curable composition 汉高股份有限及两合公司 2025-02-07 CN disclosed
CN-114423837-B Long term removable film 艾利丹尼森公司 2024-05-24 CN disclosed
CN-115427474-B Fluorinated alkoxysilyl functional polymers for antifouling and scratch-resistant coatings 阿克佐 诺贝尔国际涂料股份有限公司 2024-02-09 CN disclosed
CN-117500887-A Coated metallic effect pigments, method for the production thereof and use thereof 埃卡特有限公司 2024-02-02 CN disclosed
CN-113631624-B Curing agent composition for epoxy resin compounds, epoxy resin compounds with improved low temperature curing and multicomponent epoxy resin systems 喜利得股份公司 2023-10-20 CN disclosed
CN-112673044-B Curable composition for epoxy resin compound, epoxy resin compound and multicomponent epoxy resin system 喜利得股份公司 2023-08-15 CN disclosed
CN-116162363-A Radar frequency transparent effect pigment mixtures, formulations and coatings 埃卡特有限公司 2023-05-26 CN disclosed
WO-2013165424-A1 SOL-GEL COMPOSITIONS AND COSMETIC METHODS OF USE THEREOF AVON PRODUCTS, INC. (US) 2013-11-07 WO disclosed
US-20130291883-A1 Sol-Gel Compositions and Cosmetic Methods of Use AVON PRODUCTS, INC. (US) 2013-11-07 US disclosed
EP-2429720-A2 PHENOLATE ESTER COMPOUNDS Nano-X GmbH (DE) 2012-03-21 EP disclosed
US-20120059116-A1 METHOD OF PRODUCING PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2012-03-08 US disclosed
WO-2010130241-A2 PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2010-11-18 WO disclosed
WO-2008015123-A1 PREPARATION OF ACID DERIVATIVE-FUNCTIONAL ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed
US-20060122413-A1 Aminomethylene functional siloxanes WACKER CHEMIE AG (DE) 2006-06-08 US disclosed
US-4404014-A MICROBIOCIDES FOR TEXTILES, LUMBER, AND PLASTICS; PESTICIDES DYNAMIT NOBEL AG (DE) 1983-09-13 US disclosed
US-4254270-A INSECTICIDES, BIOCIDES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130291883-A1 Sol-Gel Compositions and Cosmetic Methods of Use KRT18, CD44, CUTA KDM4E 996/4885ALDH1A1 1869/4885POLB 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.