Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345017 | 0.69 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL20258340 | 0.68 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL7002652 | 0.67 | KDM4E (0.37) | CYP1A2CYP3A4CYP2C19KDM4ECLEC4M | |
| SCHEMBL9635290 | 0.67 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL29376920 | 0.67 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL6584701 | 0.65 | HTR3E (0.43) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL10859780 | 0.65 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL10922345 | 0.65 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL1440873 | 0.64 | HPGD (0.42) | KDM4EMAPTALDH1A1 | |
| SCHEMBL9535556 | 0.64 | ALDH1A1 (0.48) | CYP1A2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | CYP1A2 272/4885CYP3A4 88/4885CYP2C19 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.