Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498578 | 0.78 | PLAT (0.41) | KDM4ESTAT3GABRA1GABRB1GABRA3 | |
| SCHEMBL7843262 | 0.74 | RXFP1 (0.40) | KDM4EGABRA1GABRB2CLEC4MCYP1A2 | |
| SCHEMBL5773206 | 0.70 | STAT3 (0.42) | KDM4ESTAT3ALDH1A1CYP1A2HPGD | |
| SCHEMBL9487698 | 0.70 | CYP1A2 (0.56) | KDM4ESTAT3GABRA1GABRB1GABRA3 | |
| SCHEMBL7517643 | 0.68 | CYP1A2 (0.54) | KDM4EGABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL6248866 | 0.68 | PRKAB2 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL146640 | 0.67 | CYP1A2 (0.36) | KDM4ECLEC4MALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7002649 | 0.65 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL6536499 | 0.64 | ALDH1A1 (0.48) | TDP1RAB9AALDH1A1CYP3A4HPGD | |
| SCHEMBL4962609 | 0.64 | CSNK2A2 (0.49) | KDM4EALDH1A1CYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349853-A2 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | Pharmacia & Upjohn Company (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002059116-A2 | ANTIMICROBIAL QUINOLONE DERIVATIVES AND USE OF THE SAME TO TREAT BACTERIAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |