Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610478 | 1.00 | HPGD (0.37) | HPGDKMT2AEPHX1ALDH1A1MAPK1 | |
| SCHEMBL29602455 | 0.95 | MGLL (0.37) | HPGDALDH1A1MAPK1L3MBTL1POLB | |
| SCHEMBL24593481 | 0.83 | L3MBTL1 (0.41) | HPGDKMT2AALDH1A1L3MBTL1PSMB8 | |
| SCHEMBL9752033 | 0.83 | L3MBTL1 (0.41) | HPGDKMT2AALDH1A1L3MBTL1PSMB8 | |
| SCHEMBL2698690 | 0.82 | PLG (0.41) | KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL22009028 | 0.82 | BRD4 (0.39) | ALDH1A1BRD4 | |
| SCHEMBL998742 | 0.82 | PLG (0.41) | KMT2AALDH1A1POLBBRD4 | |
| SCHEMBL21754480 | 0.82 | SMN1; SMN2 (0.40) | L3MBTL1POLBBRD4 | |
| SCHEMBL13825805 | 0.81 | CA1 (0.39) | HPGDKMT2AALDH1A1PSMB8 | |
| SCHEMBL21664445 | 0.80 | NAAA (0.49) | HPGDEPHX1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9547008-B2 | Reagents for directed biomarker signal amplification | SIRIGEN INC. (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160025735-A1 | Novel Reagents for Directed Biomarker Signal Amplification | SIRIGEN GROUP LIMITED (GB) | 2016-01-28 | — | — | US | disclosed |
| US-8362193-B2 | Reagents for directed biomarker signal amplification | SIRIGEN GROUP LIMITED (GB) | 2013-01-29 | — | — | US | disclosed |