Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508647 | 0.83 | KEAP1 (0.57) | KEAP1NFE2L2ALDH1A1GAAPKM | |
| SCHEMBL2174337 | 0.82 | KMT2A (0.57) | KEAP1NFE2L2ALDH1A1GAAPKM | |
| SCHEMBL1775170 | 0.81 | PKM (0.49) | ALDH1A1GAAPKMLMNARECQL | |
| SCHEMBL8916093 | 0.81 | PKM (0.49) | ALDH1A1GAAPKMLMNARECQL | |
| SCHEMBL14664082 | 0.79 | ALDH1A1 (0.54) | KEAP1NFE2L2ALDH1A1GAAPKM | |
| SCHEMBL31298527 | 0.78 | LMNA (0.48) | KEAP1NFE2L2ALDH1A1GAAPKM | |
| SCHEMBL14665156 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GAALMNAL3MBTL1KMT2A | |
| SCHEMBL12282275 | 0.76 | PKM (0.64) | ALDH1A1GAAPKMLMNARECQL | |
| SCHEMBL2174344 | 0.76 | RECQL (0.70) | ALDH1A1GAAPKMLMNARECQL | |
| SCHEMBL13434151 | 0.74 | ALDH1A1 (0.64) | KEAP1NFE2L2ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362020-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |