Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 5/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.48 |
| ▸ | PDE1A | P54750 | 4/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643410 | 0.89 | PDE4A (0.46) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13953696 | 0.89 | PTGS2 (0.52) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13555258 | 0.87 | PDE4A (0.44) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14551480 | 0.84 | PDE4A (0.43) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14666219 | 0.84 | PDE4A (0.43) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15307678 | 0.83 | ALDH1A1 (0.51) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12416107 | 0.83 | GAA (0.51) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL129806 | 0.81 | PDE4A (0.41) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL829369 | 0.80 | KDM4E (0.52) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9596755 | 0.80 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | MAPT 4043/4885PDE4A 1363/4885PDE4B 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.