Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517334 | 0.83 | ALDH1A1 (0.32) | MAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16439846 | 0.81 | CHRNB2 (0.34) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19100879 | 0.81 | ALDH1A1 (0.31) | PIK3CAMAPTALDH1A1MTOR | |
| SCHEMBL20154949 | 0.75 | ALDH1A1 (0.34) | PIK3CAMAPTALDH1A1MTOR | |
| SCHEMBL16475111 | 0.73 | AURKA (0.42) | PIK3CAMAPTCDK2PIK3CDPIK3CG | |
| SCHEMBL14666414 | 0.72 | CYP1A2 (0.36) | MAPTLMNACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL29827390 | 0.72 | UCHL1 (0.33) | — | |
| SCHEMBL19100785 | 0.70 | DYRK1A (0.34) | MAPTCDK4CDK2 | |
| SCHEMBL31361277 | 0.69 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15788362 | 0.69 | PDE10A (0.34) | ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436168-B2 | Methods of making HIV attachment inhibitor prodrug compound and intermediates | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20130030178-A1 | METHODS OF MAKING HIV ATTACHMENT INHIBITOR PRODRUG COMPOUND AND INTERMEDIATES | BRISTOL-MYERS SQUIBB COMPANY | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030178-A1 | METHODS OF MAKING HIV ATTACHMENT INHIBITOR PRODRUG COMPOUND AND INTERMEDIATES | PFAS, APRT, TYMP | KMT2A 2728/4885PIK3CA 279/4885MAPT 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.