Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456779 | 0.87 | HSP90AB1 (0.63) | HSP90AB1ALOX5NFKB1CYP4F2CYP4A11 | |
| SCHEMBL14666294 | 0.86 | GAA (0.55) | ALOX5TRPV1NFKB1NFKB2RELA | |
| SCHEMBL14666208 | 0.84 | HSP90AB1 (0.49) | HSP90AB1ALOX5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL829369 | 0.81 | KDM4E (0.52) | ALOX5TRPV1NFKB1NFKB2RELA | |
| SCHEMBL211114 | 0.80 | SHBG (0.58) | ALOX5TRPV1NFKB1NFKB2RELA | |
| SCHEMBL930805 | 0.80 | TNKS2 (0.56) | ALOX5TRPV1NFKB1NFKB2RELA | |
| SCHEMBL1525224 | 0.79 | HSP90AB1 (0.54) | HSP90AB1ALOX5TRPV1ALDH1A1GAA | |
| SCHEMBL11215998 | 0.79 | ALDH1A1 (0.58) | HSP90AB1ALOX5NFKB1CYP4F2CYP4A11 | |
| SCHEMBL6407064 | 0.79 | CYP4F2 (0.51) | HSP90AB1NFKB1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28002484 | 0.79 | HSP90AB1 (0.54) | HSP90AB1ALOX5TRPV1NFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | HSP90AB1 1297/4885ALOX5 2982/4885TRPV1 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.