Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942871 | 0.86 | LMNA (0.43) | ALDH1A1LMNANPSR1PABPC1MAPT | |
| SCHEMBL14667409 | 0.83 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL14667394 | 0.80 | USP2 (0.63) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL15942870 | 0.79 | MAPT (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL14667398 | 0.78 | KMT2A (0.60) | LMNAMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13841477 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14667401 | 0.77 | ALOX15 (0.52) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL15942860 | 0.77 | ALOX15 (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL14667432 | 0.76 | RECQL (0.55) | MEN1KMT2AHPGDHDAC3HDAC1 | |
| SCHEMBL14667434 | 0.76 | HSD17B10 (0.38) | ALDH1A1LMNAMAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | ALDH1A1 3975/4885LMNA 2126/4885NPSR1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.