Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371039 | 0.79 | ALOX15 (0.57) | L3MBTL1CA2CA12CA1CA7 | |
| SCHEMBL28078714 | 0.78 | CTNNB1 (0.50) | CTNNB1CA2CA12CA1CA7 | |
| SCHEMBL10865257 | 0.78 | DPP4 (0.54) | CTNNB1L3MBTL1CA2CA12CA1 | |
| SCHEMBL1798 | 0.77 | CTNNB1 (0.71) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1464916 | 0.77 | CTNNB1 (0.61) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4129945 | 0.76 | CTNNB1 (0.69) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8496446 | 0.76 | CTNNB1 (0.69) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11875755 | 0.76 | CTNNB1 (0.69) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL21517637 | 0.76 | CTNNB1 (0.69) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL236889 | 0.76 | CTNNB1 (0.69) | CTNNB1L3MBTL1TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (LV) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | LTC4S, LTB4R2, LTB4R | CTNNB1 1574/4885L3MBTL1 536/4885TDP1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.