Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27800575 | 0.80 | CTNNB1 (0.77) | CTNNB1PARP10SCN9APNLIP | |
| SCHEMBL1466934 | 0.78 | CTNNB1 (0.54) | CTNNB1SOS1CA12CA1CA2 | |
| SCHEMBL23849491 | 0.76 | KDM4E (0.52) | CA12CA1CA2CA9CA7 | |
| SCHEMBL28078707 | 0.75 | MAPT (0.44) | CA12CA1CA2CA9CA7 | |
| SCHEMBL29183062 | 0.75 | MAOA (0.47) | SOS1CA12CA1CA2CA9 | |
| SCHEMBL7689367 | 0.75 | CTNNB1 (0.68) | CTNNB1SOS1PARP10CA12CA1 | |
| SCHEMBL920683 | 0.71 | CTNNB1 (0.72) | CTNNB1PARP10 | |
| SCHEMBL28078749 | 0.70 | CA12 (0.53) | SOS1PARP10CA12CA1CA2 | |
| SCHEMBL17966261 | 0.70 | CTNNB1 (0.47) | CTNNB1PARP10PNLIP | |
| SCHEMBL5159679 | 0.70 | ALOX15 (0.50) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |