SCHEMBL14670296

SCHEMBL14670296

C=C(OC)c1ccccc1C(=C)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.43
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CFTR P13569 1/20 0.41
KDM4E B2RXH2 2/20 0.40
POLB P06746 1/20 0.40
ATM Q13315 1/20 0.40
HPGD P15428 1/20 0.38
CTSD P07339 1/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA5A P35218 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
MYC P01106 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11996987 0.87 TSHR (0.59) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL25312747 0.87 ALDH1A1 (0.58) TSHRLMNAHSD17B10ALDH1A1KDM4E
SCHEMBL17875068 0.87 LMNA (0.44) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL3063615 0.85 LMNA (0.57) TSHRLMNAHSD17B10ALDH1A1KDM4E
SCHEMBL17425306 0.84 KMT2A (0.41) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL1335323 0.84 CTSD (0.53) TSHRLMNAHSD17B10HPGDCTSD
SCHEMBL12707457 0.84 ALDH1A1 (0.59) TSHRHSD17B10ALDH1A1CFTRKDM4E
SCHEMBL3698429 0.80 PTK2B (0.55) ALDH1A1KDM4EPOLBMAPTKMT2A
SCHEMBL25141448 0.80 ALDH1A1 (0.39) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL21264416 0.80 MAPT (0.35) TSHRLMNAHSD17B10ALDH1A1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367771-B2 Composition for producing organic insulator comprising an organic-inorganic metal hybrid material SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-05 US claimed
EP-3356356-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2018-08-08 EP disclosed