Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | TDO2 | P48775 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14676202 | 0.98 | SCN4A (0.50) | SCN4AIDO1TDO2LMNAHTT | |
| SCHEMBL14678017 | 0.89 | S1PR1 (0.47) | SCN4AIDO1TDO2LMNAHTT | |
| SCHEMBL16010180 | 0.86 | LMNA (0.43) | SCN4AIDO1TDO2LMNAHTT | |
| SCHEMBL14677950 | 0.81 | TACR1 (0.41) | LMNAHTTMAPTALOX12CYP3A4 | |
| SCHEMBL14675573 | 0.81 | TACR1 (0.41) | LMNAHTTMAPTALOX12CYP3A4 | |
| SCHEMBL14677066 | 0.81 | TACR1 (0.41) | LMNAHTTMAPTALOX12CYP3A4 | |
| SCHEMBL2010111 | 0.81 | IDO1 (0.60) | SCN4AIDO1TDO2LMNAHTT | |
| SCHEMBL10556268 | 0.81 | CYP19A1 (0.47) | SCN4ACYP3A4SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL17871740 | 0.80 | SLC6A2 (0.41) | LMNAHTTMAPTALOX12CYP3A4 | |
| Hydrochloric Acid SCHEMBL14676739 | 0.80 | SLC6A2 (0.41) | LMNAHTTMAPTALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902725-B2 | Heterocyclic derivatives as RORgamma modulators | GENFIT (FR) | 2018-02-27 | — | — | US | disclosed |
| US-20170349582-A1 | HETEROCYCLIC DERIVATIVES AS RORGAMMA MODULATORS | GENFIT (FR) | 2017-12-07 | — | — | US | disclosed |
| US-20140315881-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2014-10-23 | — | — | US | disclosed |
| US-20140256740-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140155419-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2014-06-05 | — | — | US | disclosed |
| EP-2736330-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2014-06-04 | — | — | EP | disclosed |
| EP-2736329-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013019621-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| WO-2013019682-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256740-A1 | COMPOUNDS AND METHODS | RORC, RORB, RORA | SCN4A 2830/4885IDO1 1484/4885TDO2 2942/4885 |
| US-20170349582-A1 | HETEROCYCLIC DERIVATIVES AS RORGAMMA MODULATORS | RORC, RORB, RORA | SCN4A 1919/4885IDO1 1036/4885TDO2 3421/4885 |
| US-20140315881-A1 | COMPOUNDS AND METHODS | RORC, RORB, RORA | SCN4A 2830/4885IDO1 1484/4885TDO2 2942/4885 |
| US-20140155419-A1 | COMPOUNDS AND METHODS | RORC, RORB, RORA | SCN4A 2830/4885IDO1 1484/4885TDO2 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.