Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL14675435 | 0.94 | BBOX1 (0.32) | TSHRALDH1A1BBOX1CYP2C19LMNA | |
| Methacrylic Acid SCHEMBL9636345 | 0.91 | TSHR (0.33) | TSHRALDH1A1CYP2C19LMNAAPEX1 | |
| Methacrylic Acid SCHEMBL1713812 | 0.87 | TSHR (0.39) | TSHRALDH1A1CYP2C19LMNAAPEX1 | |
| Methacrylic Acid SCHEMBL1874883 | 0.86 | POLB (0.33) | ALDH1A1 | |
| Methacrylic Acid SCHEMBL2059649 | 0.84 | ALDH1A1 (0.42) | TSHRALDH1A1CYP2C19LMNAAPEX1 | |
| Methacrylic Acid SCHEMBL20917781 | 0.84 | TSHR (0.38) | TSHRALDH1A1CYP2C19LMNAAPEX1 | |
| Methacrylic Acid SCHEMBL28949884 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL3467201 | 0.82 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ABBOX1 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27628757 | 0.80 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL28984262 | 0.79 | MEN1 (0.44) | TSHRALDH1A1MEN1KMT2ABBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013018356-A1 | METHOD FOR PRODUCING COMPOSITE PARTICLE, METHOD FOR PRODUCING COSMETIC, AND COSMETIC | SHIN-ETSU CHEMICAL CO.,LTD. (JP) | 2013-02-07 | — | — | WO | disclosed |