Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365939 | 0.78 | MEN1 (0.48) | KIF11MEN1KMT2ATMPRSS4NQO2 | |
| Iodide SCHEMBL5764079 | 0.75 | MEN1 (0.46) | KIF11MEN1KMT2ATMPRSS4NQO2 | |
| SCHEMBL323510 | 0.74 | KIF11 (0.48) | KIF11ALOX15ALOX12PTPN1 | |
| SCHEMBL18587158 | 0.71 | RXRA (0.57) | MEN1KMT2ATAS2R14MAPK1MAP2K4 | |
| SCHEMBL18608563 | 0.71 | FEN1 (0.44) | ALOX5APFEN1CYP2C19 | |
| SCHEMBL1290586 | 0.70 | ALOX15 (0.55) | KIF11MEN1KMT2ATMPRSS4NQO2 | |
| SCHEMBL1928764 | 0.70 | MEN1 (0.44) | ALOX5APFEN1KIF11MEN1KMT2A | |
| SCHEMBL30141994 | 0.70 | TAS2R14 (0.38) | KIF11TAS2R14MAPK1KDM4EALDH1A1 | |
| SCHEMBL3747226 | 0.70 | TAS2R14 (0.38) | KIF11TAS2R14MAPK1KDM4EALDH1A1 | |
| SCHEMBL15009854 | 0.69 | KIF11 (0.57) | KIF11PIK3CASLC22A12PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2739609-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013017654-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2013-02-07 | — | — | WO | disclosed |