Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704293 | 0.86 | KMT2A (0.50) | KMT2ATSHRKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL15514630 | 0.86 | KMT2A (0.50) | KMT2ATSHRRXFP1LMNAPKM | |
| SCHEMBL6254665 | 0.85 | LMNA (0.53) | KMT2ATSHRLMNAPKMALDH1A1 | |
| SCHEMBL8698619 | 0.83 | LMNA (0.53) | TSHRRXFP1LMNAALDH1A1GAA | |
| SCHEMBL11405723 | 0.82 | KMT2A (0.46) | KMT2ATSHRKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8751390 | 0.81 | KMT2A (0.44) | KMT2ATSHRLMNAALDH1A1HPGD | |
| SCHEMBL29222241 | 0.80 | TSHR (0.49) | KMT2ATSHRLMNAALDH1A1GAA | |
| SCHEMBL1767654 | 0.80 | KMT2A (0.44) | KMT2ATSHRLMNAALDH1A1GAA | |
| SCHEMBL11784358 | 0.80 | TGM2 (0.44) | KMT2ATSHRALDH1A1GAAHPGD | |
| SCHEMBL4196218 | 0.78 | CYP1A2 (0.47) | KMT2ATSHRALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102704-B2 | Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines | SPIROGEN SARL (CH) | 2015-08-11 | — | — | US | claimed |
| US-20140275522-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | SPIROGEN SÁRL (CH) | 2014-09-18 | — | — | US | claimed |
| CN-117580841-A | Macrocyclic compounds and uses thereof | 特修斯制药公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-2956437-B1 | ALBICIDIN DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | UNIV BERLIN TECH (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | Technische Universität Berlin (DE) | 2019-06-04 | — | — | US | disclosed |
| US-20150376120-A1 | ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS | Technische Universität Berlin (DE) | 2015-12-31 | — | — | US | disclosed |
| EP-2956774-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | Imabiotech (FR) | 2015-12-23 | — | — | EP | disclosed |
| EP-2956437-A1 | ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS | Centre de Cooperation Internationale en Recherche Agronomique pour le Developpement (FR) | 2015-12-23 | — | — | EP | disclosed |
| US-9102704-B2 | Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines | SPIROGEN SARL (CH) | 2015-08-11 | — | — | US | disclosed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014170295-A1 | COMPOUNDS POTENTIATING THE ACTIVITY OF ANTIFUNGAL DRUGS | FUNDACIÓN MEDINA. CENTRO DE EXCELENCIA EN INVESTIGACIÓN DE MEDICAMENTOS INNOVADORES EN ANDALUCÍA (ES) | 2014-10-23 | — | — | WO | disclosed |
| US-20140275522-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | SPIROGEN SÁRL (CH) | 2014-09-18 | — | — | US | disclosed |
| US-8829184-B2 | Intermediates useful for the synthesis of pyrrolobenzodiazepines | SPIROGEN SARL (CH) | 2014-09-09 | — | — | US | disclosed |
| WO-2014125112-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | IMABIOTECH (FR) | 2014-08-21 | — | — | WO | disclosed |
| WO-2014125075-A1 | ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS | Technische Universität Berlin (DE) | 2014-08-21 | — | — | WO | disclosed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | disclosed |
| US-20130035484-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PYRROLOBENZODIAZEPINES | SPIROGEN DEVELOPMENTS SÀRL (CH) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | MB, ALB, BCAT2 | KMT2A 4398/4885TSHR 3877/4885RXFP1 3054/4885 |
| US-20150376120-A1 | ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS | MB, ALB, BCAT2 | KMT2A 4398/4885TSHR 3877/4885RXFP1 3054/4885 |
| US-20140275522-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | ORC3, OXER1, SCO2 | KMT2A 2003/4885TSHR 1536/4885RXFP1 745/4885 |
| US-20130035484-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PYRROLOBENZODIAZEPINES | CYP11B2, CYP1B1, CYP11B1 | KMT2A 1249/4885TSHR 1336/4885RXFP1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.