Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468611 | 0.85 | NPC1 (0.46) | PTGS2ALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL1468623 | 0.83 | KMT2A (0.42) | ALDH1A1SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL1468627 | 0.83 | NPC1 (0.61) | ALDH1A1POLBSMN1; SMN2RAB9AMAPT | |
| SCHEMBL1468449 | 0.82 | NPC1 (0.44) | PTGS2ALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL839776 | 0.76 | PTGS2 (0.83) | PTGS2ALDH1A1POLBCYP1A2CYP2C19 | |
| SCHEMBL17199222 | 0.75 | MIF (0.46) | ALDH1A1RAB9AGAAMAPTNPC1 | |
| SCHEMBL1468613 | 0.74 | CASP3 (0.45) | ALDH1A1SMN1; SMN2GAACYP2C19MAPT | |
| SCHEMBL549592 | 0.74 | RAB9A (0.46) | PTGS2SMN1; SMN2RAB9AGAACYP2C19 | |
| SCHEMBL3971667 | 0.73 | PTGS2 (0.77) | PTGS2ALDH1A1POLBCYP1A2CYP2C19 | |
| SCHEMBL830784 | 0.72 | PTGS2 (0.75) | PTGS2ALDH1A1POLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722723-B2 | Aromatic amide derivative | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | NCOR2, NCOR1, EP300 | PTGS2 2649/4885ALDH1A1 1601/4885POLB 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.