Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470244 | 0.85 | KDM4E (0.43) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1468613 | 0.84 | CASP3 (0.45) | KMT2AMAPTALDH1A1SMN1; SMN2CASP3 | |
| SCHEMBL1467569 | 0.83 | PTGS2 (0.53) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1468187 | 0.82 | PARP1 (0.40) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL1468627 | 0.79 | NPC1 (0.61) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9409574 | 0.77 | PARP1 (0.43) | NPC1RAB9APKM | |
| SCHEMBL1350027 | 0.76 | MAPT (0.57) | KMT2AMAPTALDH1A1MEN1RAB9A | |
| SCHEMBL1468434 | 0.76 | CASP3 (0.45) | KMT2AMAPTALDH1A1SMN1; SMN2TNF | |
| SCHEMBL17199222 | 0.75 | MIF (0.46) | KMT2AMAPTALDH1A1MEN1CASP3 | |
| SCHEMBL549592 | 0.74 | RAB9A (0.46) | KMT2AMAPTMEN1SMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722723-B2 | Aromatic amide derivative | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | NCOR2, NCOR1, EP300 | KMT2A 253/4885MAPT 3909/4885ALDH1A1 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.