SCHEMBL14677150

SCHEMBL14677150

Cn1c(-c2ncccc2Cl)nc2cc(C(F)(F)F)cc(Br)c21

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 1/20 0.37
▸ PTGS2 P35354 2/20 0.35
▸ TRPV1 Q8NER1 4/20 0.35
▸ PTGES O14684 1/20 0.35
▸ PDE2A O00408 2/20 0.34
▸ PDE10A Q9Y233 2/20 0.34
▸ HSD11B1 P28845 1/20 0.34
▸ MET P08581 1/20 0.34
▸ MALT1 Q9UDY8 1/20 0.33
▸ GRM2 Q14416 1/20 0.33
▸ CASR P41180 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15868323 0.84 TRPV1 (0.36) TRPV1HSD11B1
SCHEMBL14677802 0.82 DDR1 (0.35) PTGS2TRPV1PDE2APDE10ACASR
SCHEMBL14677191 0.81 RORC (0.39) PTGS2TRPV1PDE2APDE10A
SCHEMBL17309730 0.69 MAPK14 (0.33) PTGS2TRPV1PDE2APDE10ACASR
SCHEMBL9958588 0.69 HSD11B1 (0.34) HSD11B1METCASR
SCHEMBL15933507 0.68 PTGS2 (0.41) PTGS2TRPV1PDE2APDE10ACASR
SCHEMBL29431633 0.68 PTGS2 (0.41) PTGS2TRPV1PDE2APDE10ACASR
SCHEMBL9959782 0.68 RORC (0.41) PTGS2TRPV1PDE2AHSD11B1
SCHEMBL15275082 0.68 AGPAT2 (0.45) TRPV1PDE10A
SCHEMBL9958651 0.68 HSD11B1 (0.33) PTGS2PDE2APDE10AHSD11B1MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021322-B Compositions and methods for controlling pests 住友化学株式会社 2022-04-01 — — CN disclosed
CN-112021322-A Compositions and methods for controlling pests 住友化学株式会社 2020-12-04 — — CN disclosed
EP-2952099-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-17 — — EP disclosed
EP-2952097-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
EP-2952100-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
US-20150197532-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-16 — — US disclosed
US-20150197532-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-16 — — US disclosed
US-9018134-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-28 — — US disclosed
US-9018134-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-28 — — US disclosed
WO-2014119699-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD 住友化学株式会社 (JP) 2014-08-07 — — WO disclosed
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-10 — — US disclosed
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-10 — — US disclosed
EP-2739624-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2014-06-11 — — EP disclosed
WO-2013018928-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 — — WO disclosed
WO-2013018928-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140194290-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR0B1, NR4A1, NR2C2 GPBAR1 1927/4885PTGS2 2945/4885TRPV1 2826/4885
US-20150197532-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR0B1, NR4A1, NR2C2 GPBAR1 1927/4885PTGS2 2945/4885TRPV1 2826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback