SCHEMBL17309730

SCHEMBL17309730

CCSc1cccnc1-c1nc2cc(C(F)(F)F)cc(SC)c2n1C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ PDE2A O00408 1/20 0.32
▸ PDE10A Q9Y233 1/20 0.32
▸ EIF4EBP1 Q13541 1/20 0.32
▸ PTGS2 P35354 2/20 0.31
▸ CASR P41180 1/20 0.31
▸ DDR1 Q08345 1/20 0.30
▸ TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14677802 0.88 DDR1 (0.35) MAPK14POLBPDE2APDE10APTGS2
SCHEMBL29431576 0.85 AR (0.36) MAPK14EIF4EBP1
SCHEMBL17309739 0.85 AR (0.36) MAPK14EIF4EBP1
SCHEMBL19840538 0.83 TRPV1 (0.37) POLBPDE2APDE10APTGS2DDR1
SCHEMBL14677508 0.82 HTR2B (0.39) MAPK14PDE2APDE10ADDR1
SCHEMBL14676724 0.81 POLB (0.48) MAPK14POLBPDE10APTGS2DDR1
SCHEMBL29431603 0.81 POLB (0.48) MAPK14POLBPDE10APTGS2DDR1
SCHEMBL15868310 0.77 NPC1 (0.35) PDE2APDE10ADDR1TRPV1
SCHEMBL14677382 0.76 NPC1 (0.35) PDE2APDE10ADDR1
SCHEMBL15868283 0.76 POLB (0.40) POLBPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021322-B Compositions and methods for controlling pests 住友化学株式会社 2022-04-01 — — CN disclosed
CN-112021322-A Compositions and methods for controlling pests 住友化学株式会社 2020-12-04 — — CN disclosed
EP-2952099-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-17 — — EP disclosed
EP-2952097-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
EP-2952100-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
EP-2952098-B1 PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2017-12-20 — — EP disclosed
US-9723835-B2 Pest control composition and method for controlling pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 — — US disclosed
EP-2962565-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2016-01-06 — — EP disclosed
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150366208-A1 METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
EP-2952100-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952097-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952098-A1 PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952099-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS NIT2, CRY1, CNPY2 MAPK14 3873/4885POLB 4136/4885PDE2A 187/4885
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS TH, TCOF1, BLVRB MAPK14 3567/4885POLB 4448/4885PDE2A 1062/4885
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS PNPO, NAMPT, NNT MAPK14 1076/4885POLB 4572/4885PDE2A 286/4885
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST ABAT, PNPO, GABBR1 MAPK14 2231/4885POLB 2514/4885PDE2A 895/4885
US-20150366208-A1 METHOD FOR CONTROLLING PESTS BROX, RNGTT, NOS1 MAPK14 3039/4885POLB 4136/4885PDE2A 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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