Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299177 | 0.92 | GAA (0.53) | HTTTPSAB1GAALMNAMEN1 | |
| SCHEMBL15748044 | 0.86 | CYP3A4 (0.55) | HTTTPSAB1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL25457352 | 0.84 | HTT (0.58) | HTTTPSAB1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL21301045 | 0.84 | TPSAB1 (0.44) | HTTTPSAB1ALDH1A1GAALMNA | |
| SCHEMBL21301043 | 0.83 | MEN1 (0.48) | TPSAB1ALDH1A1GAALMNAMEN1 | |
| SCHEMBL26036197 | 0.82 | TPSAB1 (0.49) | TPSAB1ALDH1A1GAALMNAMEN1 | |
| SCHEMBL23879899 | 0.82 | KMT2A (0.59) | TPSAB1ALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL16384737 | 0.82 | TPSAB1 (0.49) | TPSAB1ALDH1A1GAALMNAMEN1 | |
| SCHEMBL14677833 | 0.81 | HDAC1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL22009219 | 0.79 | TSHR (0.39) | HTTTPSAB1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081809-A1 | TRANS-CYCLOOCTENE-MODIFIED BISPECIFIC ANTIBODIES | TAMBO, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-2742153-B1 | PROTEIN AND PEPTIDE LIBRARIES | MASSACHUSETTS GEN HOSPITAL (US) | 2018-09-05 | — | — | EP | disclosed |
| EP-2742153-A1 | PROTEIN AND PEPTIDE LIBRARIES | The General Hospital Corporation (US) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013019794-A1 | PROTEIN AND PEPTIDE LIBRARIES | THE GENERAL HOSPITAL CORPORATION (US) | 2013-02-07 | — | — | WO | disclosed |