Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384737 | 0.90 | TPSAB1 (0.49) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL26036197 | 0.90 | TPSAB1 (0.49) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL1299177 | 0.88 | GAA (0.53) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL21422726 | 0.86 | TPSAB1 (0.46) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL17803834 | 0.86 | TPSAB1 (0.46) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL21301043 | 0.85 | MEN1 (0.48) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL15748044 | 0.85 | CYP3A4 (0.55) | KMT2AMEN1TPSAB1GAAALDH1A1 | |
| SCHEMBL21422711 | 0.83 | TPSAB1 (0.43) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL21301045 | 0.83 | TPSAB1 (0.44) | KMT2AMEN1LMNATPSAB1GAA | |
| SCHEMBL14677758 | 0.82 | HTT (0.57) | KMT2AMEN1LMNATPSAB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135320-B2 | Radioligands for pretargeted pet imaging and methods of their therapeutic use | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135320-B2 | Radioligands for pretargeted pet imaging and methods of their therapeutic use | FUCA1, CTSZ, TALDO1 | KMT2A 327/4885MEN1 1113/4885LMNA 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.