Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299177 | 0.86 | GAA (0.53) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL23879899 | 0.85 | KMT2A (0.59) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL16384737 | 0.85 | TPSAB1 (0.49) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL26036197 | 0.85 | TPSAB1 (0.49) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL21786938 | 0.84 | MEN1 (0.49) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL21301045 | 0.84 | TPSAB1 (0.44) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL14677758 | 0.83 | HTT (0.57) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL15748044 | 0.83 | CYP3A4 (0.55) | MEN1KMT2ATPSAB1GAALTB4R2 | |
| SCHEMBL15748539 | 0.83 | TPSAB1 (0.42) | MEN1KMT2ATPSAB1LMNAGAA | |
| SCHEMBL21422726 | 0.82 | TPSAB1 (0.46) | MEN1KMT2ATPSAB1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361098-B1 | COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET | MASSACHUSETTS GEN HOSPITAL (US) | 2019-08-28 | — | — | EP | disclosed |