SCHEMBL26036197

SCHEMBL26036197

CNC(=O)CCCC(=O)NCc1ccc(-c2nncnn2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TPSAB1 Q15661 3/20 0.49
▸ LMNA P02545 1/20 0.49
▸ GAA P10253 1/20 0.48
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ HDAC3 O15379 2/20 0.45
▸ HDAC4 P56524 2/20 0.45
▸ HDAC1 Q13547 2/20 0.45
▸ HDAC7 Q8WUI4 2/20 0.45
▸ HDAC2 Q92769 2/20 0.45
▸ HDAC10 Q969S8 2/20 0.45
▸ HDAC11 Q96DB2 2/20 0.45
▸ HDAC8 Q9BY41 2/20 0.45
▸ HDAC6 Q9UBN7 2/20 0.45
▸ HDAC9 Q9UKV0 2/20 0.45
▸ HDAC5 Q9UQL6 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ PRSS1 P07477 1/20 0.44
▸ LTB4R2 Q9NPC1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23879899 0.90 KMT2A (0.59) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL16384737 0.90 TPSAB1 (0.49) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL1299177 0.88 GAA (0.53) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL21422726 0.86 TPSAB1 (0.46) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL17803834 0.86 TPSAB1 (0.46) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL21301043 0.85 MEN1 (0.48) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL15748044 0.85 CYP3A4 (0.55) TPSAB1GAAMEN1KMT2AHDAC3
SCHEMBL21422711 0.83 TPSAB1 (0.43) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL21301045 0.83 TPSAB1 (0.44) TPSAB1LMNAGAAMEN1KMT2A
SCHEMBL14677758 0.82 HTT (0.57) TPSAB1LMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11738100-B2 Formulations and kits for radiotherapy and diagnostic imaging Clarity Pharmaceuticals Limited (AU) 2023-08-29 — — US disclosed
US-11738100-B2 Formulations and kits for radiotherapy and diagnostic imaging Clarity Pharmaceuticals Limited (AU) 2023-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11738100-B2 Formulations and kits for radiotherapy and diagnostic imaging FOLH1, GGH, CD74 TPSAB1 301/4885LMNA 3672/4885GAA 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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