Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459075 | 0.87 | LMNA (0.44) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL5519078 | 0.84 | KDM4E (0.42) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11657897 | 0.82 | KDM4E (0.54) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL28718222 | 0.77 | MMP8 (0.46) | KDM4EMEN1KMT2ALMNA | |
| SCHEMBL14727838 | 0.77 | PRKCA (0.60) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL116867 | 0.77 | LMNA (0.46) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL24436873 | 0.76 | LMNA (0.44) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL14700446 | 0.74 | KDM4E (0.43) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11231395 | 0.74 | KDM4E (0.43) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11306638 | 0.74 | KDM4E (0.43) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |