Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 4/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.41 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467991 | 0.92 | TNF (0.49) | TNFFAAHCYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1468193 | 0.87 | CYP4Z1 (0.41) | TNFFAAHCYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1468434 | 0.86 | CASP3 (0.45) | TNFFAAHCYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1467580 | 0.86 | NPC1 (0.54) | FAAHCYP4Z1CYP4F11CYP4F12GAA | |
| SCHEMBL1468412 | 0.83 | NPC1 (0.42) | FAAHRAB9ACASP1CASP7HSD17B10 | |
| SCHEMBL1470282 | 0.82 | FAAH (0.41) | TNFFAAHCYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1468089 | 0.81 | FAAH (0.46) | FAAHGAARAB9AMEN1KMT2A | |
| SCHEMBL1467554 | 0.81 | FAAH (0.46) | FAAHGAARAB9AMEN1KMT2A | |
| SCHEMBL1470284 | 0.81 | CYP4Z1 (0.41) | TNFFAAHCYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL1468601 | 0.81 | NPC1 (0.43) | MAPK1GAANPSR1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722723-B2 | Aromatic amide derivative | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | NCOR2, NCOR1, EP300 | TNF 4644/4885FAAH 2385/4885CYP4Z1 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.