SCHEMBL14680356

SCHEMBL14680356

Cc1cccc(C)c1-c1ccc2c3ccc(B4OC(C)(C)C(C)(C)O4)c4cccc(c5cccc1c52)c43

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.32
BTK Q06187 1/20 0.32
LPL P06858 1/20 0.30
LIPG Q9Y5X9 1/20 0.30
CES2 O00748 1/20 0.30
KDM1A O60341 1/20 0.30
EED O75530 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
CES1 P23141 1/20 0.30
PTPN6 P29350 1/20 0.30
BLM P54132 1/20 0.30
PTPN11 Q06124 1/20 0.30
SUZ12 Q15022 1/20 0.30
EZH2 Q15910 1/20 0.30
HIF1A Q16665 1/20 0.30
NSD1 Q96L73 1/20 0.30
EPAS1 Q99814 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14680432 0.88 LPL (0.37) JAK2BTKLPLLIPGCES2
SCHEMBL23408884 0.85 LPL (0.39) JAK2BTKLPLLIPG
SCHEMBL22534067 0.85 LPL (0.39) JAK2BTKLPLLIPG
SCHEMBL14680337 0.84
SCHEMBL14682140 0.82
SCHEMBL22727794 0.80 KDM4E (0.33) JAK2BTKLPLLIPGMAPT
SCHEMBL9943513 0.79 CYP1A2 (0.37) JAK2BTKLPLLIPGMAPT
SCHEMBL21888321 0.78 KDM4E (0.33) JAK2BTKLPLLIPGMAPT
SCHEMBL2447864 0.78 CYP1A2 (0.46) CES2KDM1AEEDPOLBMAPT
SCHEMBL29444830 0.78 CYP1A2 (0.46) CES2KDM1AEEDPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME TRPA1, OCIAD1, BMP2 JAK2 3587/4885BTK 1144/4885LPL 2035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.